|Haemophilia is an inherited bleeding disorder which occurs almost only in males. It is transmitted by unaffected female carriers to male offspring. |
It is associated with a deficiency of Factor VIII (the roman numeral stands for “8”) or a failure in Factor VIII activity which is essential for normal blood clotting. Clotting requires 25% of normal Factor VIII activity, and persons with haemophilia usually have activity levels below 5%.
Bleeding often occurs in the weight bearing joints of the body, the hip, the knee, or the ankle. It can occur in all parts of the body, particularly in a severe form of the disease with Factor VIII levels below 1%. These people bleed frequently without ever any evidence of injury.
With a Factor VIII level over 5%, bleeding is generally restricted to trauma or injury. In the case of mild haemophilia, excessive bleeding may only occur after a major injury or after surgery.
Bleeding from the bladder produces blood stained urine and in mild cases will stop of its own accord.
At the other end of the scale bleeding into the respiratory tract, the brain or the abdominal cavity can produce a surgical emergency.
Pain is generally the first indication of a bleed into a joint. Swelling of a joint to the haemorrhage can appear a day or two after the onset of pain.
Aspirin and aspirin containing drugs should not be given to a haemophiliac because aspirin also interferes with blood clotting.
Treatment of haemophilia requires infusions of Factor VIII.
Haemophiliacs may require Factor VIII before surgery or prior to dental procedures.
|Anaemia||Anaesthetics and Anaesthesia|
|Blood Pressure including Hypertension||Boils and Carbuncles|
|Bovine Spongiform Encephalopathy||Chronic Bronchitis|
|Cold Sores (Herpes Simplex)||Colostomy and Ileostomy|
|Glandular Fever (Infectious Mononucleosis)||Gout|
|Legionnaires Disease||Low Blood Pressure|
|Osteoporosis||Peptic Ulcers (Gastric or Duodenal)|
|Poor Circulation (incl Buergers & Raynauds Disease)||Prostate Problems|
|Sleeping Difficulties (Insomnia)||Slipped Disc|
|Spinal Injuries||The Common Cold|
|The Overactive Thyroid Gland||The Underactive Thyroid Gland|
|Thrombophlebitis of Superficial Veins||Thrombosis in Veins|
|Tonsillitis and Complications|
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